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  5. Activation of protease-activated receptor-2 elicits epithelialmesenchymal transition in HBE cells vi

Activation of protease-activated receptor-2 elicits epithelialmesenchymal transition in HBE cells vi

来源 :2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户：new37143
【摘 要】
：
Aims As a critical event involved in the airway remodeling,epithelial-mesenchymal transition(EMT)of bronchial epithelial cells occurs in a range of respiratory disorders such as asthma and pulmonary f
【作 者】
：
HaoGu AiGe GuYihang MaoHuang XiaoningZeng 
【机 构】
：
the First Affiliated Hospital of Nanjing Medical University
【出 处】
：
2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议
【发表日期】
：
2016年4期
【关键词】
：
airway remodeling tryptase protease-activated receptor-2 epithelial-mesenchymal 
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　　Aims As a critical event involved in the airway remodeling,epithelial-mesenchymal transition(EMT)of bronchial epithelial cells occurs in a range of respiratory disorders such as asthma and pulmonary fibrosis.Since protease-activated receptor-2(PAR2)is well documented to be implicated in airway disorders,little is known about its role in EMT so far.Our study was to determine the impact of PAR2 on EMT and illustrate the mechanisms underlying.
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