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目的 Observetheimpactofasymptomaticbronchialeosinophilicinflammationonthesmallairwayofsubjectswithallergicrhinitisandexploretheriskfactorforasthmadevelopment.方法 PatientswhovisitedENToutpatientclinicinthefirstaffiliatedhospitalofGuangzhoumedicaluniversitywererecruited.FeNO,nasallavage,spirometry,methacholinebronchialprovocationtestsandinducedsputumtestwereperformedyearlyduringfollow-upperiod.Extravisitwasrequiredwheneverhe/shehadnewlyonsetofbronchialsymptoms.