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5. Microglial phenotype contributes to beneficial effects of Interleukin-1 driven neuroinflammation in

Microglial phenotype contributes to beneficial effects of Interleukin-1 driven neuroinflammation in

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：lemon616

【摘 要】

：

Objective We previously found that sustained expression of interleukin(IL)-1b in mouse brain led to reduction in plaque pathology associated with increased evidence of glial activation,a finding that

【作 者】

：

M.Kerry O'BANION John A.OLSCHOWKA Jonathan D.Cherry 

【机 构】

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Departments of Neurobiology & Anatomy,University of Rochester School of Medicine & Dentistry,Rochest

【出 处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

Alzheimer's disease microglia interleukin-1β interleukin-4 alternative acti 

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　　Objective We previously found that sustained expression of interleukin(IL)-1b in mouse brain led to reduction in plaque pathology associated with increased evidence of glial activation,a finding that has been reproduced by others using proinflammatory stimuli.

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