Objective CCCTC-binding factor(CTCF)is a multifunctional transcription factor,which plays an important role in the development of various cancers,but its role in colorectal cancer is still unclear.
Objective Brain metastases(BM)occurs in up to 44%of non-small-cell lung cancer(NSCLC)patients and are associated with a poor prognosis with a median overall survival 4–15 months in treated patients.
Objective Multiple myeloma(MM)is the second most common hematological malignancy characterized by monoclonal proliferation of plasma cells that are derived from mature,terminally differentiated B cell