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  5. Molecular Iodine-Mediated Formal [2+1+1+1] Cycloaddition Access to Pyrrolo[2,1-a]isoquinolines with

Molecular Iodine-Mediated Formal [2+1+1+1] Cycloaddition Access to Pyrrolo[2,1-a]isoquinolines with

来源 :中国化学会第十六届全国有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：doer
【摘 要】
：
Herein,we disclosed a molecular iodine-mediated formal [2+1+1+1] cycloaddition reaction for the construction of pyrrolo[2,1-a]isoquinolines.This new reaction involves intermolecular cycloaddition of t
【作 者】
：
Shiyi Zhuang An-Xin Wu 
【机 构】
：
Key Laboratory of Pesticide & Chemical Biology,Ministry of Education,College of Chemistry,Central Ch
【出 处】
：
中国化学会第十六届全国有机合成化学学术研讨会
【发表日期】
：
2019年3期
【关键词】
：
I2-mediated Pyrrolo[2 1-a]isoquinolines One-Pot Synthesis 
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　　Herein,we disclosed a molecular iodine-mediated formal [2+1+1+1] cycloaddition reaction for the construction of pyrrolo[2,1-a]isoquinolines.This new reaction involves intermolecular cycloaddition of two in situ-generated azomethine ylides with α,β-unsaturated ketone intermediates from acetophenones and 1,2,3,4-tetrahydroisoquinolines using DMSO as a source of methylene.
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