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Based on a L.decemlineata transcriptome dataset and the data in GenBank database, a total of 74 cytochrome P450 genes (CYPs) were found.These genes fell into CYP2 clan, mitochondrial clan, CYP3 clan, and CYP4 clan, and were classified into 19 families and 35 subfamilies according to standard nomenclature.Two new families were discovered in CYP4 clan, named CYP412 and CYP413.