Objective:Surgical correction of heart defect during cardiopulmonary bypass (CPB) in neonate must be associated with extensive blood loss,dilution and transfusion.The aim of this study was to determine whether using the continuous autotransfusion system (CATS) to process packaged red cell before priming and residual blood in the CPB circuit after bypass would reduce homologous transfusion priming during neonate heart surgery and compare the effect on clinical parameters and outcome with the control group.