The BEACH-and WD40-repeat-containing protein WDR81 promotes assembly of cargo receptor and Beclin 1

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户:nicday
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Autophagic clearance of misfolded or aggregated proteins is critical to protein quality control and cellular homeostasis.
其他文献
The emerging Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe pulmonary disease in human, and represents the second example of a highly pathogenic coronavirus followed SARS-CoV.
Hepatocellular carcinoma (HCC) has become the second leading cause of cancer death worldwide.There is a compelling need for novel strategy that will improve the treatment of HCC.
Myocardial injury following ischemia/reperfusion (I/R) is a common clinical scenario in patients suffering from ischemic heart disease.
Chromokinesins play important roles in regulating genomic stability that requires faithful segregation of sister-chromosomes determined by maturation of chromosome condensation and accuracy of chromos
Although Neuregulin-1 (Nrg1) has been identified in the rat hypothalamus, localization of Nrg1 in the hypothalamus-hypophyseal structure and its corresponding functions remain unclear and need further
Nucleolus is a sub-cellular organelle that controls ribosome biogenesis, ensuring cell growth coordinated with cell proliferation.
The epithelial-mesenchymal transition (EMT) is one of the main mechanisms contributing to the onset of cancer metastasis,and has proven to be associated with breast cancer progression.
Scylla serrata reovirus (SsRV) is a major pathogen that negatively impacts mud crab (S.serrata) aquaculture.Protein p35, which is encoded by segment 10 of SsRV, contains two transmembrane (TM) parts.
Cancer stem ceils (CSCs) have been defined as a unique subpopulation in tumors that possess the ability to initiate tumor growth and sustain tumor self-renewal.
In selective autophagy, receptors are central for cargo selection and delivery.However, it remains yet unclear whether and how multiple autophagy receptors might form complex and function concertedly