Estrogen-related Enzymes and Transmembrane Transporters in Cancer of Ovary, Colon and Lung

来源 :2014第七届世界癌症大会 | 被引量 : 0次 | 上传用户:zq09171
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  The success of cancer chemotherapy is often limited by drug resistance.Among other mechanism,decreased drug uptake or enhanced efflux caused by an altered expression of transmembrane transporters and changes drug and hormones-metabolizing enzymes will reduce the intracellular concentrations of active agents and induce drug resistance.
其他文献
The term Digital Pathology has so far mostly been used to summarize technologies of generating virtual slides, archiving, visualizing and sharing them over the internet, while analysis of the actual d
会议
Kaempferol is a bioactive natural compound widely present in fruits and vegetables.Studies have identified the great potential of this flavonoid in the prevention and treatment of human cancer.Kaempfe
会议
Our long term goal is to probe the role of cellular metabolism and mitochondrial redox state in cancer transformation/progression, and identify redox imaging indices for tumor diagnosis and prognosis.
会议
Angiogenic blockage may provide a rational approach for inhibiting tumor growth.Taspine was a kind of aporphines alkaloid and was screened from Radix et Rhizoma Leonticis by a model of vascular endoth
会议
One of the most energetically demanding functions of celtular growth and division is ribosome biogenesis.Perturbations to ribosome biogenesis have been demonstrated to induce an acute stress response
会议
Strategy of immune-gene therapy based on anti-gene anti IGF-Ⅰ approach (antisense/triple helix) established in the experimental treatment of murine glioma, hepatoma andteratocarcinoma has permitted to
会议
Evading apoptosis is pivotal in both of carcinogenesis and resistance to anti-cancer therapy.We investigated the molecules and pathways of death evasion in human hepatoma cells byinduction of cellular
会议
Chronic myeloid leukemia (CML) results from expression of the constitutive tyrosine kinase activity of the BCR-ABL oncoprotien.Imatinib mesylate (IM), a molecularly targeted drug which inhibits the ty
会议
We found that tyrosine kinase inhibitors (TKIs) such as erlotinib, lapatinib, nilotinib, sunitinib, tandutinib, and icotinib could reverse ATP-binding cassette (ABC) transporter-mediated multidrug res
会议
AIM: To establish an animal model with human hepatocyte-repopulated liver for the study of liver cancer metastasis.METHODS: Cell transplantation into mouse livers was conducted using alpha-fetoprotein
会议