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Different weight ratios of PHBV/PPC composites scaffolds were constructed with two kinds of methods such as reactive melting blend and melting blend combined with porogen-leaching and alkali treatment technique.The surface morphology,porosity and biodegradability in vitro were characterized and compared.With multi-culture of Hepatoma cells Hepg-2 and scaffolds,the growth of scaffolds-cells complex was observed using scanning electron microscope.