【摘 要】
：
Objective: To investigate the feasibility of stem cells to prevent salivary gland irradiation injury,and provide a way and experimental evidence for preventing dry mouth in clinic.Methods: First,ASCs
【机 构】
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Department of Oral and Maxillofacial Surgery,Qin Du Hospital,Fourth Military Medical Xi'an 710032
【出 处】
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2014xi`an Conference of International Society for Maxillofac
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Objective: To investigate the feasibility of stem cells to prevent salivary gland irradiation injury,and provide a way and experimental evidence for preventing dry mouth in clinic.Methods: First,ASCs and BMSCs were isolated and cultured from male mice,the characteristics of two kinds of cells would be identified.Second,found an salivary gland radiation damage model, The mice were devided into 6 group,submandibular glands of every group mice were locally irradiated respectively in the head and neck region with a single dose of 0Gy,12Gy,15Gy,18Gy,21Gy,24Gy by a linear accelerator,salivary gland injury were be measured at the one week,one month,two months, three months after irradiation by measuring weight,gland function and gland morphology.
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