【摘 要】
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Background The gastrointestinal (GI) mucosal cells turnover regularly under physiological conditions, which may be stimulated in various pathological situations including inflammation.Local epithelial
【机 构】
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Department of Gastroenterology and Hepatology, The Second Affiliated Hospital, Harbin Medical Univer
【出 处】
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The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议)
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Background The gastrointestinal (GI) mucosal cells turnover regularly under physiological conditions, which may be stimulated in various pathological situations including inflammation.Local epithelial stem cells appear to play a major role in such mucosal renewal or pathological regeneration.Less is clear about the involvement of multipotent stem cells from blood in GI repair.We attempted to explore a role of bone marrow mesenchymal stromal cells (BMMSCs) and soluble stem cell factor (SCF) in GI mucosa regeneration in a rat model of inflammatory bowl diseases (IBD).
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