Dextran prevents TE-induced intracellular Ca2+ overload in isolated adult mouse ventricular myocytes

来源 :第12届生物毒素研究及医药应用学术大会 | 被引量 : 0次 | 上传用户：dfg4g4354yh

【摘要】

：

　　Intracellular Ca2+ overload plays a pivotal role in acute heart failure, which is induced by tentacle extract (TE) from jellyfish Cyaneacapillata.If an inte

【作者】

：

HuiZhang[1]QianqianWang[1]YuchenDeng[2]JiaweiGu[3]LiangXiao[1]LimingZhang[1]

【机构】

：

Department of Marine Biotechnology, Faculty of Naval Medicine, Second Military Medical University, S

【出处】

：

第12届生物毒素研究及医药应用学术大会

【发表日期】

：

2015年期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Intracellular Ca2+ overload plays a pivotal role in acute heart failure, which is induced by tentacle extract (TE) from jellyfish Cyaneacapillata.If an intervention that inhibits the increase of cytosolic Ca2+from both extracellular Ca2+ entry and intracellular Ca2+ release, it is maybe beneficial to the antagonistic effect of the cardiotoxicity of jellyfish venom.

其他文献

Transcriptome and proteome/peptidome based analysis of skin secretions from toad Bufo bufo gargariza

　　The skin of toad Bufo bufo gargarizans Cantor is still used in clinic known as Traditional Chinese Medicine in China nowadays.However, the genomic and natur

会议

An isoform of host aerolysin-type pore-forming protein (Bm-ALP3) acts as the functional inhibitor of

　　Aerolysins belong to the bacterial β-pore forming toxin superfamily.Interestingly, a diverse array of proteins harboring an aerolysin domain fused with oth

会议

Vertebrate aerolysin-type pore-formingprotein complex (βγ-CAT) prevents intracellular pathogeninvasi

　　Intracellular pathogens cause severe diseases in human and animals.The exact mechanism by which host cells effectively defend themselves against intracellul

会议

Gangliosides interact with βγ-CAT (a hostaerolysin-type pore-formingprotein complex) to modulate its

　　Aerolysins are virulence factors belonging to the bacterialβ-pore-forming toxin superfamily.βγ-CAT is a complex of an aerolysin-like protein (ALP) and tr

会议

Cyp 4A2,Apoa1,ANXA2 and DPYD are key proteinson genistein anti-fibrotic in rats

　　Objective: To investigate the molecular mechanism of genistein therapy on CCl4-induced liver fibrosis in rats by utilizing isobaric tags for relative and ab

会议

Anticancer activity of black widow spiderling extract against HeLa cells

　　Black widow spider has toxic components not only in the venom glands of the adult spider,but also in other parts of the spider body, such as legs and abdome

会议

江浙短尾蝮蛇蛇毒解离素的克隆与表达

　　解离素(Disintegrin)作为天然的整合素拮抗剂主要存在于蛇毒或水蛭毒素中，通过其分子中RGD三肽基序能够竞争性阻断整合素与其配体结合，整合素与其配体细胞外基质蛋白如层粘

会议

短尾蝮蛇蛇毒解离素整合素血小板反应蛋白细胞外基质蛋白纤维粘连蛋白生理病理过程

广西眼镜蛇蛇毒磷脂酶A2的分离纯化及其对HSC-T6细胞的作用

　　目的：对广西眼镜蛇毒中磷脂酶A2进行分离纯化并测定其对肝星状细胞HSC-T6的增值抑制作用.方法：采用Sephadex G-50凝胶层析柱、CM-Sepharose CL-6B离子交换柱、Macro-prep H

会议

四价肉毒毒素亚单位疫苗研究

　　[研究背景]肉毒毒素是肉毒梭菌产生的蛋白质,分为8个血清型A-H,其中自然存在的A、B、E和F型能够引起人类中毒.肉毒毒素有强神经毒性,属于危害性最高的A类生物战剂之一.各

会议

Antithrombotic effect of a novel tissue plasminogen activator from the venom of Gloydius brevicaudus

　　[Objective] To investigate the thrombolytic and antiplatelet effects of a novel plasminogen activator from the venom ofGloydius brevicaudusviper (GBV-PA) in

会议

Dextran prevents TE-induced intracellular Ca2+ overload in isolated adult mouse ventricular myocytes

其他学术论文