Cruciform precursor synthesis pathways - from batch to flow processes

来源 :The 14th International Conference on Microreactivity Technol | 被引量 : 0次 | 上传用户:gnaixug
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  So-called "Cruciforms" are aromatic fluorophores consisting of two perpendicular conjugated π-systems,which form a cross-like structure.They are commonly used as fluorescent materials for optoelectronics.1,2 The central aromatic core of these substances often consists of condensed heteroaromatics,such as benzobisimidazoles.3 Using flow chemistry,the productivity,selectivity and convenience of the underlying synthetic strategies is highly increased.The original batch synthesis of these heterocycles involves a series of inconvenient,dangerous,and unselective reactions,ranging from nitration to substrates containing multiple functional groups with little to no difference in reactivity.
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