FKBP51在抵制高脂诱导肥胖中的作用

来源 :第三届全国发育生物学大会 | 被引量 : 0次 | 上传用户：qingqiu12157

【摘要】

：

[目的]FKBP51是一种具有肽基脯氨酰顺-反异构酶(PPIase)活性的免疫亲和蛋白,它含有多肽重复序列结构域(TPR),能够介导蛋白与蛋白之间的相互作用。已有研究表明,FKBP51在脂肪生成中发挥重要的作用。因此,我们通过对FKBP51基因敲除小鼠表型的分析,来探究FKBP51的缺失与肥胖的关系。

【作者】

：

刘明雍伟东

【机构】

：

北京协和医学院,北京100000

【出处】

：

第三届全国发育生物学大会

【发表日期】

：

2016年8期

【关键词】

：

FKBP51 基因敲除小鼠能量代谢肝脏病理学

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FKBP51在抵制高脂诱导肥胖中的作用

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