分析多孔纳米人工骨颗粒(n-HAPA66)在修复骨缺损中的效果

来源 :第十六届全国骨肿瘤学术会议 | 被引量 : 0次 | 上传用户：qingtianleng

【摘要】

：

　　通过实验室生物安全性研究、动物实验、5年临床随访研究分析多孔纳米人工骨颗粒(n-HA/PA66)在修复骨肿瘤缺损中的效果.方法和结果：通过中国国标GB/T16886 和GB/T16175对多

【作者】

：

段宏熊燕任程张斌张闻力闵理屠重棋裴福兴

【出处】

：

第十六届全国骨肿瘤学术会议

【发表日期】

：

2015年5期

【关键词】

：

生物材料人工骨多孔纳米人工骨颗粒(n-HA/PA66) 骨缺损骨移植

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论文部分内容阅读

　　通过实验室生物安全性研究、动物实验、5年临床随访研究分析多孔纳米人工骨颗粒(n-HA/PA66)在修复骨肿瘤缺损中的效果.方法和结果：通过中国国标GB/T16886 和GB/T16175对多孔纳米人工骨颗粒(n-HA/PA66)进行实验室生物安全性研究，结果显示无毒性，无过敏反应，其溶血比率为0.59％(＜5％).在动物实验中，建立新西兰兔胫骨缺损模型并植入纳米人工骨颗粒(n-HA/PA66).术后2周，多孔纳米人工骨颗粒(n-HA/PA66)周围见新生骨小梁形成；术后12周，影像学显示缺损区密度与周围正常骨密度一致；术后26周，缺损区成熟骨小梁并重塑为板层骨.

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分析多孔纳米人工骨颗粒(n-HAPA66)在修复骨缺损中的效果

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