【摘 要】
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Background: Bacterial type Ⅳ secretion systems (T4SSs) are versatile assemblages that promote genetic exchange and/or effector translocation with consequen
【机 构】
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上海交通大学微生物代谢国家重点实验室/生命科学技术学院
【出 处】
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第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
论文部分内容阅读
Background: Bacterial type Ⅳ secretion systems (T4SSs) are versatile assemblages that promote genetic exchange and/or effector translocation with consequent impacts on pathogenesis and genome plasticity.T4SSs have been implicated in conjugation, DNA uptake and release, as well as effector translocation.The effectors injected into eukaryotic target cells can lead to alteration of host cellular processes during infection.As a well-organized, functionally flexible and comprehensive database of T4SSs is not available, we are collating available experimental and bioinformatics analyses data and the literature on known and putative T4SSs and cognate effectors in bacteria as an open-access database called SecReT4 (Type Ⅳ Secretion system Resource).
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