Lipo-alkaloid is a kind of C19-norditerpenoid alkaloids existed in Aconitum species,which usually contains an aconitane skeleton and one or two fatty acid residues.The structures are very similar to t
The Aurora kinases are a family of serine/threonine kinases that interact with components of the mitotic apparatus and serve as potential therapeutic targets in oncology.[1,2] Here we synthesized 4 se
Chirality plays a special role in drug design due to the different ways of interaction between its diverse spatial conformations and proteins.Each of enantiomers must be prepared and biologically eval