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  5. Safety and activity of blinatumomab for older patients (pts)with relapsed/refractory (R/R) B precurs

Safety and activity of blinatumomab for older patients (pts)with relapsed/refractory (R/R) B precurs

来源 :第十八届全国临床肿瘤学大会暨2015年CSCO学术年会 | 被引量 : 0次 | 上传用户：oldearth
【摘 要】
：
Objective: Treatment options for older pts with R/R ALL are limited.Blinatumomab is a bispecific T-cell engager(BiTE(R)) antibody construct that directs cytotoxic T cells to CD 19-expressing B cells,
【作 者】
：
Hagop m.Kantarjian Anthony s.Stein Ralf c.Bargou Carlos Grande Richard a.Larson Matthias Stelljes Jonathan Benjamin Catherine Jia Max s.Topp 
【机 构】
：
TX,, 1The University of Texas MD Anderson Cancer Center, Houston,
【出 处】
：
第十八届全国临床肿瘤学大会暨2015年CSCO学术年会
【发表日期】
：
2015年4期
【关键词】
：
blinatumomab older patients B precursor acute lymp 
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　　Objective: Treatment options for older pts with R/R ALL are limited.Blinatumomab is a bispecific T-cell engager(BiTE(R)) antibody construct that directs cytotoxic T cells to CD 19-expressing B cells, and is approved in the US for treatment of Ph-R/R ALL.In two phase 2 adult studies of blinatumomab (Topp MS, et al.J Clin Oncol.
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