α7相关论文
α7 nicotinic acetylcholine receptor is a potential novel therapeutic target for hepatocellular carci
Objective: Nicotine and its associated nicotinic acetylcholine receptors (nAChRs) are believed to be involved in the pro......
目的:将超声治疗方法用于脓毒症模型大鼠,并初步探讨其可能的作用机制。方法:选择78只雄性SD大鼠,按随机区组法分为假手术组(Sham组,n ......
Mesenchymal stem cells as a potential therapeutic tool to cure cognitive impairment caused by neuroi
An established contribution of neuroinflammation to multiple brain pathologies has raised the requirement for therapeuti......
蛋白酶体是桶状结构,它通过降解一系列的胞浆蛋白和核内蛋白从而在多种细胞进程中发挥作用。当蛋白酶体激活因子打开蛋白酶体的“......
神经型α7-烟碱型乙酰胆碱受体功能的不足与认知缺陷以及多种神经精神障碍相关.在动物模型中,激活α7-烟碱型乙酰胆碱受体可以提高......
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目的:研究神经母细胞瘤细胞(SH-SY5Y)α7神经型尼古丁受体基因(α7 nAChR)表达沉默后对细胞突触相关蛋白的影响,探讨α7 nAChR神经保护作......
目的研究α7尼古丁受体(nAChR)蛋白抑制对SH-SY5Y细胞tau蛋白磷酸化水平的影响及其与p38 MAPK通路的关系,探讨α7 nAChR调节tau蛋白......
目的体外探究尼古丁对人肺癌A549细胞增殖和化疗敏感性的影响。方法采用MTT法测定尼古丁对A549细胞增殖和化疗敏感性的影响。RT-PC......
Activation of α7 nAChR by PNU improves synaptic and cognitive function through restoring the express
OBJECTIVE Alzheimer disease(AD) is the most common type of dementia and is featured by the accumulation of β-amyloid pe......
The Acoustic Sensorimotor Gating Predicts the Efficiency of Hypoxic Preconditioning. Participation o
Moderate one-off hypobaric hypoxia (HBH) provokes preconditioning and prolongs the resistance (T, the time before apnoea......
目的研究p38MAPK信号传导通路激动及抑制对SH—SY5Y细胞胡神经型乙酰胆碱受体(nAChR)蛋白水平的影响并探讨受体蛋白与p38通路之间的......
阿尔茨海默病(AD)是全球老年人的主要致残、致死疾病之一。淀粉样蛋白(Aβ)级联学说是其重要发病机制之一。α7烟碱型乙酰胆碱受体(α7 ......
目的 研究SH-SY5Y神经细胞中α7 n AChR基因过表达对Ca MKⅡ和CREB的影响。方法 复苏稳定转染α7 n AChR-pc DNA3.1质粒及空载质粒......
目的构建一个含α7cDNA的真核表达载体,并在人神经胶质瘤细胞H4中进行表达.方法采用分子克隆技术将经测序证实的人α7 cDNA同真核......
Background and Objective:Increased blood pressure variability(BPV),which has been considered to cause brain damage,can b......
目的探讨培养大鼠颈上神经节神经元胆碱诱发电流的反应特征.方法在培养的大鼠颈上交感节神经元上,以α7-nAChR选择性激动剂choline......