【摘 要】
：
Early life stress (ELS) in the form of childhood neglect and/or abuse or early loss of parent has been recognised as a risk factor in the aetiology of depre
【机 构】
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UniversityofRoehamptonUK
【出 处】
：
2014第五届国际神经科技大会暨2014首届国际高科技针灸和中西医结合大会
论文部分内容阅读
Early life stress (ELS) in the form of childhood neglect and/or abuse or early loss of parent has been recognised as a risk factor in the aetiology of depression.In addition, ELS is associated with reduced effectiveness of antidepressant treatment in adulthood.In preclinical research, it is possible to model a relation between ELS and depression.In rodents, early deprivation leads to long-term neurobehavioural changes similar to those observed in clinical depression, including reduced motivation for reward.
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