【摘 要】
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As an important class ofheterocyclic compounds, pyrazoles have been studied for over a century and still continue to attract considerable attention due to the b
【机 构】
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南京航空航天大学材料学院南京210016
【出 处】
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中国化学会全国第十一届有机合成化学学术研讨会
论文部分内容阅读
As an important class ofheterocyclic compounds, pyrazoles have been studied for over a century and still continue to attract considerable attention due to the broad range of biological activities, which includes antimicrobials, analgesics,anti-inflammatory agents, CNS and oncology drugs.[1] Pyrazoles and Pyrazole derivatives are regarded as the kernel structure in a large variety of leading drugs and pesticides, such as Celebrex, Viagra, Zometapine, Cyenopyrafen, Fenpyroximate, and Tebufenpyrad et al..In addition, pyrazoles are constantly employed as building blocks in drug discovery programs, and are also found as key constituents of ligands for transition metals, receptors in supramolecular chemistry, liquid crystals, and polymers.
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