PBS/PPC生物膜的制备及相关性能评价

来源 :第九次全国口腔种植学术大会暨西湖国际口腔种植高峰论坛 | 被引量 : 0次 | 上传用户:chaosum
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  目的:采用静电纺丝法制备聚丁二酸丁二醇酯[poly(butylene succinate),PBS],聚碳酸亚丙酯(polypropylene carbonate,PPC)生物膜并评价其各项理化性能及体外降解性能.方法:采用静电纺丝法制备PBS/PPC生物膜.SEM观察其表面形态,检测其强度、接触角及体外降解过程中的PH值和失重率.结果:所制备生物膜,SEM可见呈均匀多孔状,孔孔交通,纤维直径约880nm,孔隙率为78.3%.断裂强度平均为2.31 MPa,接触角为87..体外降解第12周时PH值为6.76,失重率为6.04%.讨论:生物膜的强度和孔隙率是其发挥屏障、骨引导作用的关键因素.本研究制备的生物膜,具有良好的强度,能起到一定的空间维持能力,同时还有很高的孔隙率,利于局部血液循环,为骨再生提供营养.
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