The Notch signaling pathway has been demonstrated to play critical roles during development by specifying cell fates.In this study, we show that Notch signa
The Proliferation and differentiation of adult stem/progenitor cells into specific lineages should be precisely regulated during organ development.Hippo pat
Stable localization of signaling complex is essential for robust morphogenesis of polarized cells.Cell elongation involves molecular signaling centers which
Microglia are central nervous system (CNS)-resident macrophages and they play important roles in neural development and function.Recent studies have suggest
The mammalian post-implantation embryo has been vastly investigated at the tissue level.However, molecular characteristics of individual cells are unclear.H
A new paradigm has been established in which plants utilize proteins and RNA as non-cell-autonomously acting signaling macromolecules to mediate local and l
During embryonic lung development, epithelial tubes branch to form a complex conducting airway network.The sizes and shapes of lung epithelial tubes are cri
Rice is sensitive to chilling and thus can only be grown in certain climate-zones.Human-selection of japonica rice makes its growth-zone extend to lower yea
Understanding the genetic basis of adaptive variation and the forces that shape this diversity in natural populations are long-standing goals in evolutionar
Heterosis, the phenotypic superiority of a hybrid over its parents, has been demonstrated for many traits in Arabidopsis thaliana, but its effect on defense