【摘 要】
:
Prader-Willi syndrome(PWS)is a neuro-developmental genetic disorder characterized with obesity and hyperphagia.Most cases of PWS can be attributed to a large(5-6Mb)paternal deletion of chr15q11-q13,bu
【机 构】
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State Key Laboratory of Molecular Biology,CAS Center for Excellence in Molecular Cell Science,Shangh
【出 处】
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中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议
论文部分内容阅读
Prader-Willi syndrome(PWS)is a neuro-developmental genetic disorder characterized with obesity and hyperphagia.Most cases of PWS can be attributed to a large(5-6Mb)paternal deletion of chr15q11-q13,but the minimal deletion is mapped to the 3-untranslated region(UTR)of SNURF-SNRPN that expresses dozens of snoRNAs and several lncRNAs including sno-lncRNAs and SPAs.
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