Background People who rapidly ascend to the high altitude above 3000 mor a higher altitude than residence without adaptation will not acclimatize to high altitude in the combined effect of cold,physical overloading labour and hypobaric hypoxia that reduce tolerance hypoxiaenvironment.Most of maladaptive symptoms will disappeared due to compensatory ability in the short term.However,there are still metabolic changes and aggravatedandpersist symptoms in many people.Generally,the incidence of acute mountain sickness (AMS) increased as the increasing of altitude.The blood oxygen content due to hypoxia will reduce the adaptive compensations for body initiation,for example,the increase of heart rate and acceleration of blood flow velocity,thereby establishing the adaptive mechanism to hypoxic conditions.In case of loss of compensation,the body will have corresponding symptoms,or show the concomitant symptoms after compensating to a certain degree,among which,the changes of cardio-pulmonary functions are most obvious.The symptoms related to cardiovascular system include palpitation,shortness of breath,edema,sleep disorder,etc.We aimed to observe the alterations of right heart function bydifferentaltitudes and time phase,explore its roles in AMS and try to provide new clues and direction in clinical diagnosis,treatment and prevention for AMS.