【摘 要】
：
Purpose: Breast cancer is the most common female malignancy in Taiwan; quality of life following breast cancer therapy, though, remains rarely addressed.The aim is to evaluate quality of life among Ta
【机 构】
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Department of Medical Research and Education Division of General Surgery Cathay General Hospital SiJ
【出 处】
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(BITs 3rd Annual World Cancer Congress-2010, Breast Cancer C
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Purpose: Breast cancer is the most common female malignancy in Taiwan; quality of life following breast cancer therapy, though, remains rarely addressed.The aim is to evaluate quality of life among Taiwanese breast cancer patients with and without breast conserving therapy.Structural equation modeling with mean structural analysis, which evaluates configure invariance and compares groups on latent functional/symptomatic factor, was constructed through multi indicators approach.Materials and Methods: A total of 130 (37 with breast conserving therapy and 93 with modified radical mastectomy) females with breast cancer were enrolled.Taiwan Chinese version of European Organization for Research and Treatment of Cancer QLQ-C30 and QLQ-BR23 questionnaires were adopted as measuring instruments.Results: Patients with breast conserving therapy reported worse global quality of life status and role function scores and higher symptomatic scores in fatigue, pain, dyspnea, insomnia, appetite loss, breast and arm problem subscales.In addition, age, marital condition, hormone manipulation and post-operative adjuvant therapy were significant quality of life confounders.Measurement invariance was ascertained and the same quality of life construct could be applied to Taiwanese subjects with and without breast conserving therapy.Conclusion: Our study suggested that breast conserving therapy was associated with adverse quality of life perception for Taiwanese breast cancer survivors, mainly over worse latent symptomatic domain factor, with lower between-group mean.
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