Biology of olfactory entheashing cells in CNS regeneration

来源 :中国神经科学学会第九届全国学术会议暨第五届会员代表大会 | 被引量 : 0次 | 上传用户:q999666
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  Olfactory ensheathing cells (OECs) are restricted to the primary olfactory system and are thought to be a unique class of glial cells.During development, OECs envelop olfactory axons as they project from the olfactory epithelium to the bulb.They differ from typical glia by virtue of the fact that they are present in both the peripheral nervous system (PNS) and the central nervous system (CNS), and share some features and functions of astrocytes as well as Schwann cells.It is generally accepted that OECs contribute to the growth and targeting of olfactory axons during normal cell turnover and after injury.OECs have also emerged as prime candidates for cell transplant strategies for repairing neural lesions.In the present study, we will discuss some molecular and cellular mechanisms of OECs on CNS regeneration.
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