The objective of the study was to examine the incidence of sepsisinduced jaundice in cirrhotic patients and its impact on mortality.Sepsis was the most frequent underlying reason for jaundice (n =58,43.3％).Patients with sepsis-induced jaundice had higher MELD (model for end-stage liver disease) score on admission and peak international normalized ratios (INR) on admission, and higher one-year mortality (15.5％ versus 4.9％ in patients without sepsisinduced jaundice, P=0.000).The rate of complication was also higher in patients with sepsis-induced jaundice (31％ vs.10％ in those without sepsis-induced jaundice; P=0.021).Sepsis-induced jaundice is common in patients with liver cirrhosis and is associated with higher mortality.