【摘 要】
：
Aim: Total glucosides of paeony (TGP), an active compound extracted from the roots of Paeonia lactiflora Pall, was a valuable herb used in the treatment of RA.However, TGPs slow effects seriously limi
【机 构】
：
Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory an
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
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Aim: Total glucosides of paeony (TGP), an active compound extracted from the roots of Paeonia lactiflora Pall, was a valuable herb used in the treatment of RA.However, TGPs slow effects seriously limit its application in clinic.Paeoniflorin (Pae), as the the main active ingredients in TGP, is assimilated poorly after oral administration, which causes the slowly effects of TGP.In the present study, a active derivative of Pae was synthesized, and its anti-inflammatory & immunomodulatory activities were studied as well.
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