【摘 要】
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The aim of this study was to analyze outcomes in adult patients with early stage systemic anaplastic large-cell lymphoma (ALCL) treated with doxorubicin-based chemotherapy and radiotherapy.Forty-six a
【机 构】
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Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Pe
论文部分内容阅读
The aim of this study was to analyze outcomes in adult patients with early stage systemic anaplastic large-cell lymphoma (ALCL) treated with doxorubicin-based chemotherapy and radiotherapy.Forty-six adult patients with early stage systemic ALCL received chemotherapy followed by radiotherapy.All patients except two received chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or a CHOP-like regimen.Twenty patients had stage Ⅰ disease, and 26 patients had stage Ⅱ disease.The 5-yr overall survival (OS), progression-free survival (PFS), and local control rates for all patients were 84.4%, 63.6%, and 90.8%, respectively.The 5-yr OS and PFS rates were 95.0% and 77.4% for Ann Arbor stage Ⅰ disease, and 75.1% and 51.7% for stage Ⅱ disease, respectively.Lymph node involvement was the main pattern of disease progression or relapse for these patients.Adult patients with early stage systemic ALCL treated with doxorubicin-based chemotherapy and radiotherapy had a favorable prognosis.
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