GRP78 promotes EMT and cell-matrix adhesion via autocrine TGF-β/Smad2/3 signaling

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户:btbsh023
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Coloretal cancer (CRC) is the human digestive system malignancy and its incidence is increasing with years.Metastasis of colon cancer is the main reason of the therapy failure.
其他文献
  目的 诱导并建立耐长春新碱(VCR)的入骨肉瘤细胞株并探讨其耐药机制。方法 采用逐步增加药物剂量冲击诱导方法诱导人成骨肉瘤MG63细胞株;CCK-8法检测亲本与耐药细胞株对VC
  Renal fibrosis is the final outcome of all progressive kinds of chronic kidney disease.The aim to explore the mechanism and block the progress of renal fibr
会议
  细胞驱动蛋白KIF11能在有丝分裂时期将中心粒分离。抑制KIF11可激活caspase-3而引起细胞凋亡,但其信号通路相关机制尚未知晓。为了弄清这一细胞死亡通路,我们以人胚肾细胞H
  CD147 is highly expressed in tumor tissues and on the membrane of tumor cells.Our previous studies have proved that the interaction of CD147 with integrin c
会议
  Directional migration of sperm to oocyte is the prerequisite for successful fertilization.In most animal species, motile sperm are attracted by chemical fac
会议
  Herbicide acetochlor after application enters both surface and underground waters, so that the equilibrated acetochlor concentrations in rivers and streams
会议
  The transcription factor KLF5 is highly expressed in basal triple-negative breast cancer (TNBC) and promotes breast cancer cell proliferation, survival and
会议
  DNA双加氧酶Ten-Eleven Translocation(TET)是新发现的一类重要的表观遗传修饰因子,其通过将DNA序列中的5-甲基胞嘧啶(5mC)氧化为5-羟甲基胞嘧啶(5hmC),进而调控基因的转
  Chondroitin sulfate proteoglycans (CSPGs) are up-regulated in the microenvironment of the glial scar after spinal cord injury (SCI), as a key inhibitory fac
会议
  Escherichia coli (E.coli) is the leading cause of neonatal gram-negative bacterial meningitis, but the pathogenesis of E.coli meningitis remains elusive.
会议