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酶作为生物催化剂对生物产业具有重大影响，但其较低的生物学稳定性限制了其广泛应用，因此探求蛋白质稳定化作用机制、建立有效的蛋白质稳定化策略是科研工作者密切关注的热点。由于蛋白质结构的复杂性，尚未发现通用的蛋白质稳定化机制。
酶活性中心区域改造有效提升酶热稳定性
【摘 要】
：
酶作为生物催化剂对生物产业具有重大影响，但其较低的生物学稳定性限制了其广泛应用，因此探求蛋白质稳定化作用机制、建立有效的蛋白质稳定化策略是科研工作者密切关注的热
【机 构】
：
上海交通大学生命科学与技术学院,微生物代谢国家重点实验室,上海200240;吉林大学分子酶学工程教育部重点实验室,长春130023上海交通大学生命科学与技术学院,微生物代谢国家重点实验室,上海2002
【出 处】
：
2013年第四届全国“跨学科蛋白质研究”学术讨论会
【发表日期】
：
2013年10期
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