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5. Orphan nuclear receptor TR3 induces autophagic cell death of melanoma via a mitochondrial signaling

Orphan nuclear receptor TR3 induces autophagic cell death of melanoma via a mitochondrial signaling

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：heguojing514

【摘 要】

：

Melanoma is the most aggressive form of skin cancer with notorious resistance to apoptosis, which is a major barrier to the successful melanoma treatment.In 201

【作 者】

：

Qiao Wu Tianwei Lin 

【机 构】

：

StateKeyLaboratoryofCellularStressBiology,SchoolofLifeSciences,XiamenUniversity,Xiamen361005,FujianP

【出 处】

：

中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

：

2014年8期

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Melanoma is the most aggressive form of skin cancer with notorious resistance to apoptosis, which is a major barrier to the successful melanoma treatment.In 2011, FDA approved two new therapeutics for melanoma,vemurafenib and ipilimumab.

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