Multivalent Drug Design for the Detection and Treatment of Degenerative Diseases

来源 :第十三届中国国际多肽大会 | 被引量 : 0次 | 上传用户:piliwuhen
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Studies utilizing genomics and proteomics have demonstrated that multiple changes in the expressed genomes and proteomes occur for most of our degenerative diseases,such as cancer,cardiovascular disease,mental disease,prolonged and neuropathic pain,addiction,etc.These changes strongly suggest that new approaches to drug design are necessary to address the disease state,and for these reasons,we have developed several new approaches.
其他文献
  This review describes recent trends in novel stationary phases for peptide separation.There are various ways to separate crude peptide,but during the last f
  The current project aimed at the peptide drug target discovery and new drug molecular design.It broaden the application of drug molecule design to the field
  Detection and regulation of amyloids aggregation are of great importance in diagnosing and understanding the amyloidogenesis.Here,by utilizing the fluoresce
  The membrane-bound mucin MUC1 glycoprotein is an attractive target for tumor immunotherapy.The tandem repeat sequence of MUC1: HGVTSAPDTRPAPGSTAPPA,has been
  Marine organisms have yielded a diverse array of biologically active peptides that could eventually be developed into therapeutic agents.Structure elucidati
  Currently used μ opioid analgesics(e.g.morphine)produce limiting side effects and are ineffective for treatment of neuropathic pain.Recent pharmacological
氯代有机物广泛应用于工业、农业和人类的日常生活中,这类有机物通过各种途径进入环境水体中.因为许多氯代有机物有毒,且在自然界中难于降解,这类物质在环境中的暴露对人类和
  Phosphinopeptides are important phosphorus analogs of naturally occurring peptides.Sulfonopeptides are significant sulfur analogs of naturally occurring pep
会议
摘要:后主李煜用血泪之词表达了国破家亡的不幸和哀愁,词中口语的运用更是增添了词的真实色彩,在不加雕饰的语言中充满着作者的真情实感,读罢让人不得不为这位出身特殊的词人而感叹,同时又感动。   关键词:李煜词;语言;口语  中图分类号:G633.3 文献标识码:A 文章编号:1992-7711(2018)11-0127  李煜词以其极高的艺术成就在词史上具有很大的影响力。在南唐词人中,甚至是整个唐五
中国篆刻艺术是以汉字的篆书为基础文字,以印材为载体,以篆法、章法、刀法为创作要素,表现文字美、线条美、构图美、刀法美、意象美的造型艺术作品。所谓古玺,是战国以前的玺