Increased expression of TMEM16A/Ano1 chloride channel associated with diabetic erectile dysfunction

来源 :泌尿生殖肿瘤华夏医学论坛2016暨长城国际泌尿男科转化医学论坛2016 | 被引量 : 0次 | 上传用户:tom0101
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective: To investigate the presence,location and functional role of TMEM16A/anotamin-1 (Ano1) calcium-activated chloride channel (CaCC) in the penile of rats with diabetic erectile dysfunction.Methods: Eight-week-old male Sprague-Dawley (SD) rats were administrated streptozotocin (diabetic) or citrate buffer (control) randomly.
其他文献
Objective: To obtain systematic and comprehensive evidence regarding the benefits and safety of PDE5i compared to those of placebo.Methods: All randomized controlled trials (RCTs) reporting on the eff
Objective: To analyze the patency and natural pregnancy rate after the microsurgical vasoepididymostomy,the influence of the anastomosis site on the patency rate in the patients of obstructive azoospe
Objective: To evaluate the clinical effects of the vesiculoscopy and related endoscopic technique on the treatment of ejaculatory duct obstruction (EDO) and severe,persistent hematospermia in cases th
Objective: The study aimed to explore the relationship between premature ejaculation (PE) and the serotonin transporter gene-linked polymorphic region (5-HTTLPR) with respect to the biallelic and tria
Objective: To investigate firstly the relationship between semenogelin Ⅰ (Sg Ⅰ) expression and seminal vesiculitis.Seminal vesiculitis is one of the most common diseases in male urogenital system.Howe
Objective: Seminal vesiculitis is the common disease of male urogenital system.However,the pathogenesis of seminal vesiculitis remains unclear.Semenogelin Ⅰ (Sg Ⅰ) is mainly synthesized and secreted b
Objective: This study was designed to evaluate the efficacy of combination therapy of Tamoxifen,L-carnitine and daily PDE5 inhibitors and to compare with Potassium para-aminobenzoate (Potaba) monother
Objective: The introduction of nerve-sparing radical prostatectomy represents a milestone in the treatment of prostate cancer.However,a certain percentage of cancer survivors still suffer from erectil
Objective: For patients with diabetes,erectile dysfunction (ED) is common and greatly affects quality of life.However,these patients often exhibit a poor response to first-line oral phosphodiesterase
Objective: A Korean herbal formulation,Ojayeonjonghwan,is used to treat late-onset hypogonadism (LOH) symptoms including erectile dysfunction (ED).A previous study demonstrated that a modified Ojayeon