论文部分内容阅读
Nearly 100 billion neurons and hundred kinds of neurotransmitters exist in the brain with varying distributions in different brain regions [1].Getting knowledge of such distributions is very important for distinguishing the neurological mechanisms of these regions.Since neurons communicate with each other through discharge and neurotransmitter release,high-sensitive neural sensors are needed to scan the neural activities in different brain regions both electrophysiologically and electrochemically.Recent advances in nanotechnology offer a unique opportunity to integrate nanostructures on the surfaces of microelectrode array neural sensors [2,3],which can greatly increase the effective surface area of the microelectrodes,decrease the electrical background noises and amplify the neurotransmitter oxidation currents.