Expression,Purification and Kinetic Studies of Metallo-β-Lactamase VIM-2

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户:curtises
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Verona integrin-encoded(VIM)is one of the most clinically significant MβLs because they appear in bacterial strains that most commonly found in the clinic.
其他文献
  Hypoxia,which results from an inadequate oxygen supply in the body,has been associated with various diseases,such as tumors,cardiac ischemia,stroke and vasc
  Cysteine is especially attractive for site-specific chemical modification owing to its high nucleophilicity at physiological conditions and relatively low n
  Bismuth and its compounds are considered relatively non-toxic and hence have found increasing application in chemical synthesis,catalysis and medicine.
  Cystathionine β-synthase(CBS)and cystathionine γ-lyase(CSE)are responsible for producing hydrogen sulfide(H2S)in mammals.
  Inositol hexakisphosphate(IP6)has been found to be associated with ubiquitination mediated protein degradation.
  Maleimide analogue,5-methylene pyrrolones(5MPs)are highly thiol-specific and tracelessly removable bioconjugation tools.
  The selective detection of Cu2+and S2-in pure water system has been very challenging.
  As the most abundant transitional metal in human body,iron is the essential component of variable proteins and enzymes and is associated with a variety of b
  β-Lactamases catalyzed hydrolysis of β-lactam antibiotics,such as penicillins,cephalosporins,and carbapenems,and are the most widespread bacterial resista
  RNA labeling is crucial for study of RNA structure and metabolism.Here we report N6-allyladenosine(a6A)as a new small molecule for RNA labeling through both