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  5. P2X7 Receptor Participation in the Activation of NLRP3 Inflammasome in Trigeminal Ganglia of Dural I

P2X7 Receptor Participation in the Activation of NLRP3 Inflammasome in Trigeminal Ganglia of Dural I

来源 :2015中国老年医学和老年健康产业大会 | 被引量 : 0次 | 上传用户：jwhyyx
【摘 要】
：
BACKGROUND: Migraine is a common neurovascular disorder in the clinical and its pathogenesis is very complicated.This study aimed to investigate whether NLRP3 inflammasome is activated in a rat model
【作 者】
：
X.H.Li L.Z.Chen L.Huang Q.Wu L.Chen Q.Wan 
【机 构】
：
Department of Neurology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
【出 处】
：
2015中国老年医学和老年健康产业大会
【发表日期】
：
2015年7期
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BACKGROUND: Migraine is a common neurovascular disorder in the clinical and its pathogenesis is very complicated.This study aimed to investigate whether NLRP3 inflammasome is activated in a rat model of dura inflammatory stimuli which can simulate the migraine attack, and to explore whether P2X7 receptor (P2X7R) is involved in NLRP3 activation.
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