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Rapid and early identification of crop stress and disease is essential for the effective management of crop and improvement of crop yield.In this study,we describe a paper-based microfluidic sensor for the rapid and early identification of crop stress and disease.Our approach makes use of hybridization-meditated target capture using a miniaturized colorimetric probe.The colorimetric probe enables visual identification of the crop stress and disease without the need for sophisticated instruments or the multiple incubation.