Hematopoietic Stem Cell Transplantation in treatment of Philadelphia Chromosome-Positive Acute Lymph

来源 :中华医学会血液学分会第九次全国造血干细胞移植学术会议 | 被引量 : 0次 | 上传用户:wangyanling100wang
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background Ph+ ALL is a high-risk subset of ALL that has an extremely poor prognosis Since the introduction of TKI to combination chemotherapy regimens, the majority of newly diagnosed Ph+ ALL patients achieve CR However, long-term outcomes in adults remain unsatisfactory without allogeneic HSCT
其他文献
子宫内膜异位症概念:子宫内膜异位症(内异症)是指子宫内膜组织(腺体和间质)在子宫腔被覆内膜及子宫以外的部位出现、生长、浸润,反复出血,继而引发疼痛、不孕及结节或包块等.常见妇科疾病:患病率2院内患者的研究1.5%基于人群的研究;8%-15%基于特点:病变广泛、形态多样极具侵袭性和复发性性激素依赖
会议
" The important role of intestinal flora in various outcomes after allogeneic BMT has been recognized for many decades in both mouse and man.Recent technologies such as 16S RNA-sequencing and whole ge
会议
Although the long-term disease control rate after myeloablative chemotherapy with allogeneic hemopoietic stem cell transplantation (allo-HSCT) is high, the benefit is typically offset by high treatmen
会议
Mesenchymal stem cells (MSC) are known to accumulate at the sites of inflammation as well as damaged tissues.MSCalso possess an immunomodulatory activity, and therefore MSCcan be utilized for the trea
会议
High-Risk AML/MDS----Great challenge of Transplantation allo-HSCT is a potentially curative therapy for patients with high-risk AML/MDS.Significant advances in therapeutic approaches, including the us
会议
Proportion of elderly population (age 65 ≤)is rapidly growing in Japan Characteristics of aged HSCs Low repopulation potential Less homing Myeloid lineage bias Higher risk of malignant transformation
会议
Currently, standard GvHD prophylaxis in matched sibling donor allogeneic hematopoietic stem cell transplant is the combination of short course methotrexate and calcineurin inhibitor including cyclospo
会议
Immunopathogenesis of GVHD Central role of CD4+ T cells in GVHD Recent studies on Th22/IL-22 in GVHD Administration of IL-22 enhanced thymus recovery in mouse after total body irradiation.(Science 201
会议
Leukemia remains a serious disease with high morbidity and mortality Elizabeth W,et al.CA Cancer J Clin.2014 Cornelissen JJ,et al.Blood,2007allo-HSCT is an effective treatment for leukemia Allo-HSCT t
会议
Background During the last years, hematopoietic stem cell transplant from haploidentical donor is increasing by using the unmanipulated graft.We report an update of the results of allogeneic bone marr
会议