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Objective Anti-endothelial cell antibody (AECA) has been well known to reflect endothelial injury.Meanwhile,graft-versus-host disease (GVHD),a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT),is also closely associated with endothelial injury.We hypothesized that AECA might be associated with GVHD.