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Purpose Diffuse large B cell lymphoma (DLBCL) is the most common Non-Hodgkin Lymphomas.The clinical and pathological heterogeneity of this entity makes prognostic assessment difficult.Gene expression profiling (GEP) studies have demonstrated that DLBCL can be reproducibly divided into germinal center B-cell-like (GCB),activated B-cell-like (ABC),and type 3.