Shedding of Syndecan-4 from vascular endothelial cells induces endothelial dysfunction and impaires

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户:ZYYZH
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Background Syndecan-4(synd4),a ubiquitous cell surface heparin sulfate proteoglycan,functions as an independent receptor for numerous cellular processes through signaling pathways.In the study,we investigated whether synd4 shedded from vascular endothelial cells in diabetes mellitus (DM) and the role it played in the pathogenesis of impaired angiogenesis.
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