Effects of 5F on cytotoxicity,apoptosis and cell cycle in human liver cancer cells

来源 :2012医学科学前沿暨第二届个体化治疗与抗肿瘤药物研究新趋向研讨会 | 被引量 : 0次 | 上传用户：yfzzx

【摘要】

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【作者】

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YE Hua ZHEN Xue-bao LI Li LV Ying-nian LIANG Nian-ci

【机构】

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Guangdong Key Laboratory for Research and Development of Natural Drugs,Guangdong Medical College,Zha

【出处】

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2012医学科学前沿暨第二届个体化治疗与抗肿瘤药物研究新趋向研讨会

【发表日期】

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2012年11期

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　　Objecive:To investigate the anticancer effect of ent-11 α-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F),a compound isolated from Pteris semipinnata L (PsL),in human liver cancer Hep3B cells.Methods:Hep3B cells were treated with 5F (0-80 μg/ml) for different time periods.Cytotoxicity was examined using a MTT method.Apoptosis was examined using Annexin V-EGFP staining and caspase-3 activity.Cell cycle was examined using propidium iodide staining.

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Effects of 5F on cytotoxicity,apoptosis and cell cycle in human liver cancer cells

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