转录因子KLF7调控TNNI2基因转录活性的研究

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：s83436776

【摘要】

：

Krüppel样转录因子7(Krüppel-like factor,KLF7)负调控脂肪细胞分化,但其靶基因尚不清楚。本研究前期利用ChIP-seq技术,发现KLF7在鸡快骨骼肌亚型肌钙蛋白I(fast skeletal muscle Tronponin I,TNNI2)基因-7308 nt处存在一个富集区域,提示TNNI2可能为KLF7的一个靶基因。采用ChIP-qPCR技术针对前期ChIP-s

【作者】

：

孙婴宁金钊盛和宇王维禹王宁

【机构】

：

齐齐哈尔大学生命科学与农林学院,齐齐哈尔,161006;东北农业大学动物科学技术学院,哈尔滨,150030

【出处】

：

中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

：

2018年10期

【关键词】

：

鸡 Kruppel样转录因子7(KLF7) 快骨骼肌亚型肌钙蛋白I(TNNI2) 转录活性前脂肪细胞

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转录因子KLF7调控TNNI2基因转录活性的研究

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