ASIC1a regulates insular long-term depression and is required for extinction of conditioned taste av

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:daiguisheng613
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  The synaptic function of acid-sensing ion channel 1a(ASIC1a)is emerging to be understood.Here,we identify a crucial role of ASIC1a in synaptic plasticity at mouse insular synapses.Whereas genetic ablation and pharmacological inhibition of ASIC1a reduced the induction probability of long-term depression(LTD),they did not affect long-term potentiation in insular cortex.
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