【摘 要】
:
In the present study,the spatiotemporal pattem of chicken retinal ganglion cells firing activity in response to full-field white light stimulation was investigated.Cross-correlation analysis showed th
【机 构】
:
Department of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
【出 处】
:
中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the
论文部分内容阅读
In the present study,the spatiotemporal pattem of chicken retinal ganglion cells firing activity in response to full-field white light stimulation was investigated.Cross-correlation analysis showed that ganglion cells of sustained subtype fired in precise synchrony with their adjacent neurons of the same subtype (delay lag within 2 ms,narrow correlation).On the other hand,the activities of neighboring ganglion cells of transient subtype were correlated with distributed time lags (10-30 ms,medium correlation).Pharmacological studies demonstrated that the intensity of the medium correlations could be strengthened when exogenous GABA was applied,and attenuated when GABA receptors were blocked by picrotoxin.Meanwhile,the GABAergic modulation on the narrow correlations was not consistent.These results suggest that in the chicken retina,GABAergic pathway(s) are likely involved in the formation of medium correlations between ganglion cells.Neurons might fire at a lower rate but with higher level of synchronization to improve the efficiency of information transmission,with the mechanism involving the GABAergic inhibitory input.
其他文献
Pain is a multidimensional conscious experience including sensory and affective components.The former has been extensively studied,while the latter is poorly understood.Accumulating evidence from morp
It is well known that initial consolidation requires de novo gene transcription and protein synthesis in order for memory to become stable.The consolidated memory again becomes labile and temporarily
In this research,we investigated striatal neurogenesis in 3,6,12 and 18-month old rats after cerebral ischemic injury.All rats were subjected to a 20 min middle cerebral artery occlusion (MCAO),given
Negative bHLH transcription factor Hesl can inhibit neural stem cells (NSCs) from precocious neurogenesis through repressing proneural gene expression; therefore,sustenance of Hesl expression is cruci
Nicotine has been shown to improve cognition in humans and in animal models.Hippocampal long term potentiation (LTP) is a useful synaptic model of learning and memory.Previous in vitro and in vivo stu
Neuronal microcircuitry represents the communications between various individual neurons,mainly consisting of chemical synaptic transmissions and serving as the foundation of functional neural network
Dopamine,as an important neuromodulator in the vertebrate retina,exerts its actions through two classes of receptors,known as the D1 and D2 receptors.In this work,localization of D1 receptors in carp
Morphological and electrophysiological features of the GABAergic substantia gelatinosa (SG) neurons in the caudal spinal trigeminal nucleus (the medullary dorsal horn; MDH) were examined in the GAD67-
The experimental scorpion BmK (Buthus martensi Karsch) sting test has been demonstrated to be an available inflammatory animal pain model to understand the mechanisms of the tonic spontaneous response