【摘 要】
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Cancer and other rapidly proliferating cells require cholesterol and other membrane components to optimize growth.High density lipoprotein (HDL) have been implicated in cholesterol delivery in some ma
【机 构】
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Department of Surgery, Northern Clinical School, The University of Sydney Australia
论文部分内容阅读
Cancer and other rapidly proliferating cells require cholesterol and other membrane components to optimize growth.High density lipoprotein (HDL) have been implicated in cholesterol delivery in some malignancies, including breast cancer, ovarian cancer, adrenocortical tumors, and prostate cancer.Apolipoprotein A-II (ApoA-II) is the second most abundant lipoprotein in plasma where it binds and shrinks a subset of HDL, which is predominantly depressed in pancreatic cancer patient sera.
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