Impacts of supplementation with omega-3 fish oil on bone mineral density: a two-year randomized cont

来源 :第七届国际骨质疏松及骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户:smalldong224
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Background: To determine the effects of treatment with an anti-inflammatory dose of fish oil on bone mineral density (BMD).Methods: In a multicenter, double-blind RCT (ACTRN 12607000415404), 202 Australian participants with knee osteoarthritis aged ≥ 40 years (median age (range), 61 (41-87) years;49% female) received either low-dose fish oil (providing eicosapentaenoic acid (EPA)+docosahexaenoic acid (DHA) 0.45g/day) or high-dose fish oil, providing EPA+DHA 4.5g/day) for two years.
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